OpenEvidence Secures $210M Series B at $3.5B Valuation to Expand AI Medical Platform for Physicians

OpenEvidence, the AI-powered medical search engine built exclusively for physicians, has raised $210 million in a Series B funding round, bringing its valuation to $3.5 billion. The round was co-led by Google Ventures and Kleiner Perkins, with continued support from Sequoia Capital and participation from Coatue, Conviction, Thrive, and others.

Founded by Daniel Nadler, Ph.D., OpenEvidence has quickly become one of the most widely used medical platforms in the U.S., with more than 40% of clinicians using the tool across over 10,000 hospitals and medical centers. The platform offers instant, evidence-based clinical answers powered by proprietary generative AI trained on peer-reviewed content from trusted partners including the AMA, JAMA, and the New England Journal of Medicine.

With usage surpassing 8.5 million monthly consultations and growing by 65,000 verified clinicians each month, OpenEvidence continues to scale rapidly. Alongside the funding, the company also launched DeepConsult, an advanced AI agent that autonomously analyzes vast medical literature to deliver Ph.D.-level research summaries for clinicians.

Designed to combat physician burnout and information overload, OpenEvidence positions itself as the trusted, high-speed AI co-pilot for modern clinical decision-making — offered free to all verified U.S. doctors.

James Dargan

James Dargan is a writer and researcher at The AI Insider. His focus is on the AI startup ecosystem and he writes articles on the space that have a tone accessible to the average reader.

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