OpenEvidence, a Miami-based AI company focused on clinical decision support for physicians, has closed a $250 million funding round that doubled its valuation to $12 billion. The financing was led by Thrive Capital and DST, following earlier participation from Sequoia Capital, Google Ventures, Nvidia, Kleiner Perkins, Craft Ventures, and Mayo Clinic.
Founded in 2022 by Daniel Nadler and Zachary Ziegler, OpenEvidence trains AI systems on peer-reviewed medical literature and real-world clinical feedback from verified physicians. The company reports that more than 40% of U.S. doctors now use the platform, which is offered free to clinicians and monetized through advertising. OpenEvidence generated over $100 million in annualized revenue last year and plans to remain independent as it deepens adoption across small and mid-sized medical practices.
